Saint Polyxenia was born in Spain, lived in the first century after the Nativity of Christ, and was a disciple of the holy Apostles. She embraced Christianity after the preaching of Saint Apostle Paul. Polyxenia was abducted by a pagan and taken to Greece, where, by God's grace, she remained unharmed. In Greece, she met Saint Apostle Peter and was then hidden from her captor in the city of Patras, where she was baptized by Saint Apostle Andrew the First-Called.
Polyxenia witnessed the sufferings of Saint Andrew, who, despite his torments, continued to preach. His words deeply touched her, and she was strengthened in her faith. After the death of Saint Andrew, she decided to preach Christianity and returned to Spain with Saint Onesimus to convert her fellow countrymen.
For nearly forty years, Saint Polyxenia actively spread Christianity, setting an example of a pious life. She and her sister Xanthippe converted many pagans to Christianity. Saint Polyxenia peacefully reposed around the year 109 after the Nativity of Christ, preserving her virginity until the end of her life.
